Recombinant Human Serum Albumin Solution, 200 mg/mL
Recombinant human serum albumin solution, 200 mg/mL, is an animal origin-free liquid cell culture supplement supplied sterile-filtered for research and bioprocessing workflows. CCM-RG-0081 is provided as a 50 mL format for laboratories that require a concentrated albumin source with defined composition, controlled handling, and procurement-ready documentation. The product is listed at $2,866.67 and ships on blue ice with free worldwide shipping where available.
- ✓ Free worldwide shipping
- ✓ ISO-aligned manufacturing
- ✓ Certificate of Analysis on request
- ✓ Bulk & custom volumes quoted on request
Overview
CCM-RG-0081 is a 200 mg/mL recombinant human serum albumin solution for use as a defined protein supplement, carrier protein, and stabilizing excipient in cell culture reagent systems. The liquid format supports direct dilution into qualified media, buffers, and process-development formulations, reducing preparation time compared with weighing and dissolving dry albumin. It is classified as animal origin-free and supplied sterile-filtered, making it suitable for laboratories moving toward chemically defined or reduced-serum workflows.
Key release specifications include liquid form, sterile-filtered presentation, pH 6.0–8.0, and a 12-month shelf life when stored as directed. The 50 mL pack size is appropriate for R&D screening, media optimization, pilot-scale formulation studies, and controlled reagent qualification before larger purchasing decisions. For related defined supplements and formulation components, see our cell culture reagents category.
Applications
- Supplementation of mammalian cell culture media where a recombinant albumin source is preferred over serum-derived albumin.
- Protein carrier or stabilizer in media, buffer, cytokine, growth-factor, or lipid-delivery formulations used in research cell culture workflows.
- Process-development studies requiring animal origin-free raw materials and consistent lot documentation.
- Serum-reduction and chemically defined media optimization for adherent, suspension, and primary research cell systems, subject to user qualification.
- Bioprocessing support for cell expansion, recombinant protein expression studies, and formulation screening where albumin concentration, sterility, and pH range are critical inputs.
Storage and Handling
Store CCM-RG-0081 at 2–8 °C protected from light. The product ships on blue ice to help maintain refrigerated conditions during transit. Upon receipt, inspect the container, confirm that the solution remains clear and within the expected condition, and return it promptly to refrigerated storage. Use aseptic technique after opening, minimize repeated warm-up cycles, and record in-use dating according to internal laboratory procedures. Do not use beyond the stated 12-month shelf life unless an internal stability assessment supports the application.
Quality and Documentation
CellCultureMedia supplies CCM-RG-0081 for research and bioprocessing teams that require specification-driven purchasing, traceable documentation, and predictable logistics. Manufacturing and quality release are managed using ISO-aligned quality practices, with lot-specific Certificate of Analysis support available on request through our quality documentation channel. For price confirmation, multi-unit requirements, and standing supply programs, submit details through request a quote. Standard online orders include free worldwide shipping where available, with blue-ice shipment for this refrigerated liquid reagent.
Specifications
Storage & Handling
Storage: 2~8 ℃, protected from light. Shelf life: 12 months. Ship cold-chain where required.
Quality & Documentation
Manufactured under ISO-aligned quality management systems. Full documentation — Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), formulation summary, and stability data — is available on request. Email [email protected] with the SKU.
About this product
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- Bovine Serum in Cell CultureBovine serum is the liquid fraction of clotted cattle blood, added to culture medium at 5-10% to supply growth factors, hormones, transport and attachment proteins, lipids and trace elements that basal media do not contain. Fetal bovine serum (FBS) and fetal calf serum (FCS) are two names for the same product, collected from the fetus at slaughter of pregnant cows; newborn calf serum comes from calves under about 20 days old and donor bovine serum from controlled donor herds aged roughly 12-36 months, both containing more immunoglobulin and fewer growth factors than FBS. Because serum is an undefined biological material with substantial lot-to-lot variation, unresolved animal welfare questions and a volatile supply chain, defined serum-free and animal-origin-free media are increasingly preferred where the cell line will tolerate them.
- Heat Inactivation of Fetal Bovine Serum (FBS)Heat inactivation of fetal bovine serum is a controlled 30-minute incubation at 56 degrees C that destroys the heat-labile proteins of the complement cascade before the serum is added to culture medium. The serum is thawed, brought to 37 degrees C, transferred to a 56 degrees C water bath, held for exactly 30 minutes from the moment the serum itself reaches temperature with gentle swirling every 5-10 minutes, then cooled immediately and aliquoted. For routine culture of established cell lines it is usually unnecessary, because complement activity in fetal serum is low and heating also degrades labile growth factors; it remains standard practice for immunological assays and complement-sensitive cells.
- Recombinant Human Albumin in Cell CultureRecombinant human serum albumin (rHSA) is a 585-amino-acid, 66.5 kDa non-glycosylated protein produced in yeast such as *Pichia pastoris* or in transgenic rice rather than purified from human plasma, and it is used as an animal-origin-free supplement in serum-free and chemically defined culture media. In culture it works as a carrier for fatty acids, lipids, hormones and trace elements, as an antioxidant through its free cysteine-34 thiol, as a scavenger that sequesters toxic metals and excess free fatty acids, and as a shear-protective surface-active protein in stirred and sparged culture. Typical working concentrations are 0.1-10 g/L, most often 0.5-5 g/L, and it is commonly supplied as a 200 mg/mL (20%) solution. Its performance depends heavily on what is bound to it, so fatty-acid-loaded and fatty-acid-free preparations behave quite differently.
- Recombinant Human Insulin in Cell CultureRecombinant human insulin is a 51-amino-acid, 5.8 kDa two-chain protein used as a core supplement in serum-free and chemically defined culture media, where it drives glucose and amino acid uptake, protein and lipid synthesis, and cell survival. It is produced in *E. coli* or yeast rather than extracted from animal pancreas, making it animal-origin-free, and is usually supplied as a zinc-stabilised dry powder. The typical working concentration is 5-10 ug/mL, the level delivered by a standard 1X ITS supplement, which is roughly a thousandfold above physiological insulin levels -- at that concentration insulin acts substantially through the IGF-1 receptor as well as its own. Because insulin is poorly soluble near neutral pH, powder must be dissolved in dilute hydrochloric or acetic acid before dilution into medium.
