BIT Serum Substitute, 100 mL

CCM-RG-0076 is a ready-to-use liquid BIT serum substitute for cell culture additive programs requiring controlled supplementation for hematopoietic stem cell models and related suspension or semi-suspension culture systems. The product is classified as animal-origin and is intended for laboratory cell culture, assay development, scale-up evaluation, and process comparison studies where lot documentation, defined release specifications, and procurement continuity are important. It is supplied in a 100 mL bottle for convenient use in R&D, pilot, and media optimization workflows.

The formulation is specified with a pH range of 7.0–8.0 and osmolality of 280–340 mOsmol/kg, supporting compatibility with common mammalian cell culture media within typical physiological operating ranges. The product is filter-sterilized, with endotoxin controlled at ≤3 EU/mL and a stated shelf life of 36 months when stored as directed. For teams sourcing adjacent supplements and handling reagents, additional options are available in our cell culture reagents category.

• Supplementation of hematopoietic stem cell culture systems during media screening, expansion studies, and comparative serum-reduction experiments.
• Use as a liquid additive in animal-origin workflows where a serum substitute format is preferred for consistency, handling simplicity, and controlled input documentation.
• Evaluation in custom media development programs where pH, osmolality, sterility, endotoxin, and shelf-life specifications must be reviewed before adoption.
• Support for academic, biotech, and biopharma R&D laboratories preparing small-batch culture media, assay plates, or early process development batches.
• Procurement consolidation for laboratories requiring a 100 mL reagent size with documented storage, dry ice shipping, and quotation support through request-quote procurement.

Store CCM-RG-0076 at -30 to -5 °C and protect the bottle from light. Shipments are prepared on dry ice to maintain the frozen temperature profile during transit. Upon receipt, confirm that frozen material and packaging condition are acceptable, then transfer immediately to qualified frozen storage. Avoid repeated freeze-thaw cycles where possible; aliquot under aseptic conditions if repeated access is expected. Mix gently after thawing until the liquid is uniform, and do not use if visible contamination, unexpected turbidity, or container damage is observed. Follow your site’s validated aseptic handling procedures for introduction into complete media or experimental feed solutions.

CellCultureMedia supplies CCM-RG-0076 for professional cell culture and bioprocess research workflows with specification-driven release information. Manufacturing and quality practices are ISO-aligned, and product documentation can be reviewed for sterility method, endotoxin limit, pH range, osmolality range, format, storage, and shelf-life requirements. A Certificate of Analysis is available on request for qualified orders, and customers may consult our quality documentation resources before procurement review. The list price for the 100 mL size is $694.44. Free worldwide shipping is available for eligible destinations, with dry ice service selected for this frozen reagent.